产品货号：
Z14009
中文名称：
CSN8/COPS8抗体
英文名称：
Anti-CSN8/COPS8 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CSN8/COPS8 Antibody |
| 指标别名 | COP9;COP9 homolog;COPS8;COPS8/COP9;CSN8;hCOP9;SGN8;Signalosome subunit 8 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | COPS8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CSN8 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human CSN8.The immunogen is located within the last 50 amino acids of CSN8. |
| 计算分子量 | 23kDa |
| 成分 | CSN8 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CSN8 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The COP9 signalosome (CSN) is an evolutionarily conserved protein complex of the eight subunits that interacts with deubiquitinating enzymes and protein kinases and is highly homologous to the lid sub-complex of 26S proteasome.The CSN complex is an essential regulator of the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes,which leads to a decrease in ubiquitin ligase activity of SCF-comlpexes such as SCF,CSA or DDB2.It is also involved in phosphorylation of p53,c-jun/JUN,ITPK1 and IRF8/ICSBP,possibly via its association with CK2 and PKD kinases.CSN8 encodes the smallest and the least conserved but first identified subunit of CSN.Recent studies show CSN8 is essential for Drosophila development and is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence. |
| Uniprot ID | Q99627 |
| 基因名全称 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) |
| 蛋白名全称 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) |
| 推荐稀释比 | CSN8 antibody can be used for detection of CSN8 by Western blot at 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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